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Website report · 1 h ago

www.nature.com

“Neoadjuvant botensilimab with or without balstilimab in pMMR and dMMR colon cancer: the phase 2 UNICORN trial | Nature Medicine”

Template-written 44 evidence items Code reader analysed 18 scripts
What this means for you

Nature talked to 11 outside services on a first visit, including 6 that measure visits or show ads.E12E13E18E16

  • An AI agent used the site and saw 1 of 2 claimed features working.E42E44E42
  • Live data / analytics: The quoted text comes from the cookie consent banner and describes analytics cookies, not a data product. The article's Metrics page did load figures that update over time: 3,378 accesses, Altmetric attention counts and percentile ranks, a list of news mentions, and a 'Last updated' timestamp.E42E44
  • A working app / platform: Here 'umbrella/platform phase 2 trial' describes how the clinical trial (NCT05845450) was designed. It does not refer to a software app or platform. The page is an open-access journal article with no interactive tool to try, and the trial itself happens outside the website.E42
  • Also noticed, Site is a peer-reviewed journal article: The page is a Nature Medicine research article on the UNICORN colon cancer trial. It is not a crypto or AI project site, so the quoted 'claims' were taken from general page text.E42
  • Tech check: the site claims live data / analytics and a working app / platform, and its public page shows matching evidence.E39E40E33E34E35
  • Before you click anything, the page loads analytics or ad services: Google Analytics / Tag Manager and Google Ads / DoubleClick.E12E13E18E16E19E17
  • 7 cookies were set in your browser, all by the site itself.E20E21E22E23E24

Tech check

What the site says about itself, next to what its public page actually loads. Facts only, no verdict: you decide.

Evidence found

Live data / analytics

“…low video information to be shared for both marketing, analytics and editorial purposes. By accepting optional cookies,…”E39

Live connections: receives a live stream of updates from a serverE33

Calls to its own backend: /platform/contextual, /exposed-detailsE34E35

Evidence found

A working app / platform

“…label, non-randomized, window-of-opportunity, umbrella/platform phase 2 trial testing short-course preoperative treatm…”E40

Calls to its own backend: /platform/contextual, /exposed-detailsE34E35

Live connections: receives a live stream of updates from a serverE33

Calls its own backend /platform/contextual, /exposed-detailsE34E35
Wallet code none seen
Contract calls in its code none seen
Talks to AI services none seen
Live connections receives a live stream of updates from a serverE33

The real tech may live elsewhere. This page links to: github.com/SegataLab/preprocessing · check the code github.com/sottorivalab/rescope · check the code github.com/sottorivalab/UNICORN_ST_analysis · check the code github.com/Natera-TMED/Unicorn · check the code github.com/andrewalmonte/UNICORN · check the code

What the AI agent tried

An AI agent (claude-opus-5-5) used the site in our sandbox for 3 steps and saw 1 of 2 claimed features working. It can't connect a wallet, pay, sign or log in, so those features count as "couldn't test". What it reports is what it observed, not a verdict.

Seen working

Live data / analytics

The quoted text comes from the cookie consent banner and describes analytics cookies, not a data product. The article's Metrics page did load figures that update over time: 3,378 accesses, Altmetric attention counts and percentile ranks, a list of news mentions, and a 'Last updated' timestamp.E42E44

Couldn't test

A working app / platform

Here 'umbrella/platform phase 2 trial' describes how the clinical trial (NCT05845450) was designed. It does not refer to a software app or platform. The page is an open-access journal article with no interactive tool to try, and the trial itself happens outside the website.E42

Also noticed

Things the agent saw along the way that aren't among the site's claims. Not counted above.

Noticed

Site is a peer-reviewed journal article

The page is a Nature Medicine research article on the UNICORN colon cancer trial. It is not a crypto or AI project site, so the quoted 'claims' were taken from general page text.E42

Noticed

Ad network calls before cookie choice

The cookie banner was still showing, with no choice made, when the page sent requests to pagead2.googlesyndication.com and ep1.adtrafficquality.google.E43E44

What it is

  • The Internet Archive first saved this site on 1996-10-18 (10974 days ago).E41
  • The site describes itself as: “Preoperative immune checkpoint inhibitors (ICIs) are active in patients with deficient mismatch repair (dMMR) colon cancer (CC), whereas pro”E2
  • Notable building blocks in its code: Firebase SDK.E27
  • In your browser it saves small bits of data in your browser and receives a live stream of updates from a server.E32E33
  • It has sections such as /info, /articles, /nm, /siteindex, /saved-research and /search.E37E38
  • While loading, it called 2 endpoints on its own servers, such as /platform/contextual and /exposed-details.E34E35

Where your data goes

Analytics & trackingCount visits and record what you do on the page. 1
www.googletagmanager.comGoogle Analytics / Tag Manager: Google's visitor analytics and tag loader 1×E12
AdvertisingShow ads and follow you across sites to target them. 5
pagead2.googlesyndication.comGoogle Ads / DoubleClick: Google's ad network (serving and measuring ads) 22×E13
ep2.adtrafficquality.googleGoogle Ads / DoubleClick: Google's ad network (serving and measuring ads) 3×E18
ep1.adtrafficquality.googleGoogle Ads / DoubleClick: Google's ad network (serving and measuring ads) 2×E16
tpc.googlesyndication.comGoogle Ads / DoubleClick: Google's ad network (serving and measuring ads) 2×E19
748c875ca5e5b1c3f1ce3d58a6e20493.safeframe.googlesyndication.comGoogle Ads / DoubleClick: Google's ad network (serving and measuring ads) 1×E17
Not identifiedServices we don't have in our list yet. 5
media.springernature.comnot identified 5×E9
injections.readcube.comnot identified 2×E11
content.readcube.comnot identified 1×E10
crossmark-cdn.crossref.orgnot identified 1×E15
scripts.webcontentassessor.comnot identified 1×E14

How key features work

Live updates

It keeps live connections open (server-sent events) so content updates without reloading.E33

event_source

Loading its content

Its content loads from its own API while you browse (/platform/contextual and /exposed-details).E34E35

/platform/contextual/exposed-details

Measuring what you do

Visits and clicks are measured with Google Analytics / Tag Manager, Google Tag Manager, Meta Pixel, Segment and 1 more (found in its traffic or its code).E12E28E29E30E31

Google Analytics / Tag ManagerGoogle Tag ManagerMeta PixelSegmentHotjar

How ads get picked

Ads are chosen through ad networks and exchanges (Google Ads / DoubleClick); they receive details about your visit to bid on the ad space.E13E18E16E19

Google Ads / DoubleClick

Saving data on your device

It saves data in your browser (localStorage), so some things persist between visits.E32

local_storage

Cookies and storage

Names only. We never store the values.

CookieSet forKeptWhose
csrf-tokenE20nature.com about 1 daysthe site
idp_sessionE21nature.com until you close the browserthe site
idp_session_httpE22nature.com until you close the browserthe site
idp_markerE23nature.com about 400 daysthe site
CONTENT_USAGE_SESSIONIDE24nature.com until you close the browserthe site
user.uuid.v2E25www.nature.com about 92 daysthe site
snccE26nature.com about 365 daysthe site

Pages and API calls

Pages it links to

/info/articles/nm/siteindex/saved-research/search/subjects/naturecareers/authors/auth/nm.rss/cgi-bin//npg_/support/nature-portfolio/reprints/openresearch/product/media-kits/immersive/natafrica/nindia/nmiddleeast/briefings41591-026-04710-1

Endpoints

Called while loading (seen) or named in the code (code).

www.nature.com/platform/contextualseenE34
idp.nature.com/exposed-detailsseenE35
www.google.com/ccm/geocodeE36

Evidence

Every sentence above points to one of these. Code references show the file, line:column and the short identifier that matched, never the site's code itself.

E1
Page title: Neoadjuvant botensilimab with or without balstilimab in pMMR and dMMR colon cancer: the phase 2 UNICORN trial | Nature Medicine
page title · https://www.nature.com/articles/s41591-026-04710-1
E2
Page description: Preoperative immune checkpoint inhibitors (ICIs) are active in patients with deficient mismatch repair (dMMR) colon cancer (CC), whereas proficient mi
page description · https://www.nature.com/articles/s41591-026-04710-1
E3
Site name: Nature
page site_name · https://www.nature.com/articles/s41591-026-04710-1
E4
Main heading: Neoadjuvant botensilimab with or without balstilimab in pMMR and dMMR colon cancer: the phase 2 UNICORN trial
page h1 · https://www.nature.com/articles/s41591-026-04710-1
E5
14 request(s) to www.nature.com
types: 4 font, 3 script, 2 document
GET https://www.nature.com/articles/s41591-026-04710-1 · font · 14 requests · network recording
E6
3 request(s) to idp.nature.com
types: 2 document, 1 xhr
GET https://idp.nature.com/authorize · document · 3 requests · network recording
E7
1 request(s) to cmp.nature.com
types: 1 script
GET https://cmp.nature.com/production_live/en/consent-bundle-8-latest.js · script · network recording
E8
2 request(s) to sgtm.nature.com
types: 1 script, 1 image
GET https://sgtm.nature.com/gtm.js · script · 2 requests · network recording
E9
5 request(s) to media.springernature.com
types: 5 image
GET https://media.springernature.com/full/nature-cms/uploads/product/nm/header-95e59e63930e5d6009bad2c23a42ab2d.svg · image · 5 requests · network recording
E10
1 request(s) to content.readcube.com
types: 1 script
GET https://content.readcube.com/ping · script · network recording
E11
2 request(s) to injections.readcube.com
types: 2 script
GET https://injections.readcube.com/config.json · script · 2 requests · network recording
E12
1 request(s) to www.googletagmanager.com
types: 1 script
GET https://www.googletagmanager.com/gtm.js · script · network recording
E13
22 request(s) to pagead2.googlesyndication.com
types: 14 fetch, 7 script, 1 other
GET https://pagead2.googlesyndication.com/tag/js/gpt.js · fetch · 22 requests · network recording
E14
1 request(s) to scripts.webcontentassessor.com
types: 1 script
GET https://scripts.webcontentassessor.com/scripts/93dabb8d80079a87fec7bb6f67b807fce90e1688f8957ad7ad152bfd58ea01c2 · script · network recording
E15
1 request(s) to crossmark-cdn.crossref.org
types: 1 script
GET https://crossmark-cdn.crossref.org/widget/v2.0/widget.js · script · network recording
E16
2 request(s) to ep1.adtrafficquality.google
types: 1 xhr, 1 image
GET https://ep1.adtrafficquality.google/getconfig/sodar · xhr · 2 requests · network recording
E17
1 request(s) to 748c875ca5e5b1c3f1ce3d58a6e20493.safeframe.googlesyndication.com
types: 1 document
GET https://748c875ca5e5b1c3f1ce3d58a6e20493.safeframe.googlesyndication.com/safeframe/1-0-45/html/container.html · document · network recording
E18
3 request(s) to ep2.adtrafficquality.google
types: 1 script, 1 document, 1 image
GET https://ep2.adtrafficquality.google/sodar/sodar2.js · script · 3 requests · network recording
E19
2 request(s) to tpc.googlesyndication.com
types: 2 image
GET https://tpc.googlesyndication.com/simgad/14489228520723732537 · image · 2 requests · network recording
E20
Cookie 'csrf-token' set for nature.com
kept for about 1 days
cookie csrf-token on nature.com · value not stored
E21
Cookie 'idp_session' set for nature.com
session cookie
cookie idp_session on nature.com · value not stored
E22
Cookie 'idp_session_http' set for nature.com
session cookie
cookie idp_session_http on nature.com · value not stored
E23
Cookie 'idp_marker' set for nature.com
kept for about 400 days
cookie idp_marker on nature.com · value not stored
E24
Cookie 'CONTENT_USAGE_SESSIONID' set for nature.com
session cookie
cookie CONTENT_USAGE_SESSIONID on nature.com · value not stored
E25
Cookie 'user.uuid.v2' set for www.nature.com
kept for about 92 days
cookie user.uuid.v2 on www.nature.com · value not stored
E26
Cookie 'sncc' set for nature.com
kept for about 365 days
cookie sncc on nature.com · value not stored
E27
Firebase SDK found in the code
sgtm.nature.com/gtm.js @ 482:487 · “firebase_” · pattern scan
E28
Google Tag Manager found in the code
www.nature.com/ (page HTML) @ 11:317 · “googletagmanager.com/gtm.js” · pattern scan
E29
Meta Pixel found in the code
sgtm.nature.com/gtm.js @ 25:348 · “connect.facebook.net/en_US/fbevents” · pattern scan
E30
Segment found in the code
sgtm.nature.com/gtm.js @ 15:71435 · “cdn.segment.com” · pattern scan
E31
Hotjar found in the code
cmp.nature.com/production_live/en/consent-bundle-8-latest.js @ 1:37765 · “Hotjar” · pattern scan
E32
Uses the browser ability: local_storage
saves small bits of data in your browser
www.nature.com/oscar-static/js/global-article-es6-bundle-f2e8a58cc7.js @ 1:22904 · “localStorage.setItem(” · pattern scan
E33
Uses the browser ability: event_source
receives a live stream of updates from a server
www.nature.com/oscar-static/js/global-article-es6-bundle-f2e8a58cc7.js @ 1:15640 · “new EventSource(” · pattern scan
E34
The page called /platform/contextual on www.nature.com (GET)
GET https://www.nature.com/platform/contextual · xhr · network recording
E35
The page called /exposed-details on idp.nature.com (GET)
GET https://idp.nature.com/exposed-details · xhr · network recording
E36
Code reader found the endpoint www.google.com/ccm/geo
how: call:A.fetch
s07-gtm.js · “www.google.com/ccm/geo” · the code reader
E37
111 links to pages on the same site
page links · https://www.nature.com/articles/s41591-026-04710-1 · /info, /articles, /nm, /siteindex, /saved-research, /search, /subjects, /naturecareers, /authors, /auth, /nm.rss, /cgi-bin
E38
Code reader found the route s41591-026-04710-1
www.nature.com/articles/s41591-026-04710-1 @ 10:20 · “s41591-026-04710-1” · the code reader
E39
The site says: “…low video information to be shared for both marketing, analytics and editorial purposes. By accepting optional cookies,…”
page text · https://www.nature.com/articles/s41591-026-04710-1 · …low video information to be shared for both marketing, analytics and editorial purposes. By accepting optional cookies,…
E40
The site says: “…label, non-randomized, window-of-opportunity, umbrella/platform phase 2 trial testing short-course preoperative treatm…”
page text · https://www.nature.com/articles/s41591-026-04710-1 · …label, non-randomized, window-of-opportunity, umbrella/platform phase 2 trial testing short-course preoperative treatm…
E41
The Internet Archive first saved nature.com on 1996-10-18 and has snapshots from 2000 different days
page web archive · https://web.archive.org/web/19961018174308/nature.com
E42
Agent step 1: view
AI agent step 1 · view on /articles/s41591-026-04710-1
E43
Agent step 2: click Metrics details (not done: Locator.click: Timeout 4000ms exceeded.)
AI agent step 2 · click on /articles/s41591-026-04710-1 · page called GET pagead2.googlesyndication.com/gampad/ads, GET pagead2.googlesyndication.com/pcs/view, GET pagead2.googlesyndication.com/pagead/gen_204, GET pagead2.googlesyndication.com/pcs/activeview
E44
Agent step 3: go /articles/s41591-026-04710-1/metrics
AI agent step 3 · go on /articles/s41591-026-04710-1/metrics · page called GET pagead2.googlesyndication.com/pagead/gen_204, GET pagead2.googlesyndication.com/pcs/activeview, GET idp.nature.com/exposed-details, GET pagead2.googlesyndication.com/gampad/ads, GET pagead2.googlesyndication.com/pcs/view, GET ep1.adtrafficquality.google/getconfig/sodar

Limits

  • We only see what your browser sees: code and requests on a first visit, without logging in or accepting cookie banners. What the servers do with data is invisible from outside.
  • Site code is usually minified (compressed), so names are partly lost and some code may be only partly analysed.
  • Some trackers only load after you accept cookies or log in, so the real list can be longer.
  • We visited from a server in the United States. Sites load different trackers and cookie banners in different countries (visitors in the EU usually get a consent banner first).
  • The tech check compares the site's own words with what its public page loads. Work done on servers, in private code or in separate apps isn't visible here, so 'nothing found' means not visible on the public page, not that it doesn't exist.
  • This text was written from fixed templates because no AI writer was available. It uses exactly the same evidence.
  • The code reader hit its size budget on parts of 5 large bundle file(s); those parts weren't fully analysed.

Facts, not judgements: this page describes what the code and traffic show, not anyone's intent. Not financial advice. Case id e3yLSGYe.